Dr. H.M.M. Heleen van Beusekom, PhD, FESC. Experimental Pathobiologist; Team leader for Experimental vascular interventions and vascular repair. Head Histology & MS Imaging Lab at Experimental Cardiology, Erasmus MC University Medical Center.

Brief summary of research over the last five years. My work focusses on micro- and macro-vascular injury and repair in cardiovascular disease. Thrombosis is essential in initiating myocardial infarction, acute ischemic stroke atherosclerosis, and plays an important role in vascular healing. Recently it was discovered that NETs, neutrophil extracellular DNA traps with toxic properties, play an important role in thrombus formation and subsequently also in myocardial infarction and stroke. We are building the MRCLEAN and CONTRAST national biobanks for acute ischemic stroke, and the local CorTAsk biobank containing peri-procedural plasma and thrombus aspirates retrieved during routine treatment for STEMI.

Professional memberships and output. Dr. van Beusekom is a Fellow of the European Society of Cardiology since 2012, and member of the working groups “Atherosclerosis and Vascular Biology” and  “Thrombosis” and the “Stroke Council”. She is also a member of the “International Working group on Intracoronary OCT” the “Dutch Pathology Society”, the “Dutch society of Mass Spectrometry” and the “Mass spectrometry Imaging Society”. She is an editorial board member of “Eurointervention” and Section editor for basic science and experimental cardiology for “Cardiology Journal”.  Scopus ID: 7004104745. Google Scholar: H-factor 37

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Max van der Kolk
Scientific programmer
Computational Science Lab, University of Amsterdam

After graduating in mechanical engineering in 2015, I started my PhD research in the Structural Optimisation and Mechanics group at Delft University of Technology. My research aims to apply topology optimisation, a form of structural design optimisation, to the automated design of high-precision optical instruments. This design process is driven by large-scale gradient-based optimisation combined with computational mechanics to find material distributions to optimise a design's performance. During this work, I greatly enjoyed combining numerical modelling with mathematical programming and developing their numerical implementations, bringing me to my current position as scientific programmer at the Computational Science Lab, University of Amsterdam. Nowadays, I focus on developing numerical models with various applications in the field of computational biomedicine. Outside work, I like to go bouldering and tinker with software.



Keywords:
numerical modelling; mathematical programming

Francesco Migliavacca obtained a MSc in Mechanical Engineering in 1992 and a PhD in Bioengineering in 1997 both from Politecnico di Milano. He worked as a Research Assistant at the Cardiothoracic Unit of Great Ormond Street Hospital for Children in London in 1994 and 1997-99. At present he is a Full Professor of Bioengineering in the Department of Chemistry, Materials and Chemical Engineering ‘Giulio Natta’ of Politecnico di Milano and the Coordinator of the Section of Biological Engineering. Between 2007 and 2018 he was the Director of the Laboratory of Biological Structure Mechanics (LaBS) of the Politecnico di Milano. His major research activities have included the fluid dynamic optimization of pediatric cardiac surgery procedures, fluid dynamics in the living systems as well as structural analysis and material behavior of biomedical devices, in particular intravascular stented devices. He received the medal 'Le Scienze 2001' in Engineering and was awarded the European Society of Biomechanics Perren Award in 2004. He is Associate Editor of the peer-reviewed journals ‘Cardiovascular Engineering and Technology’ and ‘Frontiers in Pediatric Cardiology’.

Keywords: stents – mathematical modelling – biomechanics